Wioletta Czaja, PhD, Assistant Professor and head of the DNA Repair and Genome Stability lab at The Hormel Institute has been awarded $1.3 million in funding for a research grant (R01) titled, “Role of HELLS chromatin remodeler in genome maintenance” from the National Institute of General Medical Sciences, National Institutes of Health.
Dr. Czaja’s research will involve investigating epigenetic and chromatin-based regulation of DNA repair and genome stability.
The project will investigate the role of the conserved HELLS ATP dependent chromatin remodelers in regulation of DNA repair and genome stability. HELLS has been implicated in many cancers including leukemia, glioblastoma, prostate, and hepatocellular carcinoma.
For this research, Dr. Czaja is collaborating with Rafael Contreras, PhD, Assistant Professor and head of the Genome Instability and Chromosome Biology lab at The Hormel Institute; Anja-Katrin Bielinsky, PhD, of the University of Minnesota; and Zachary Lewis, PhD, of the University of Georgia. The grant funding started on September 1, 2021 and goes through May 31, 2025.